Is Midlife Obesity an Alzheimer Disease Risk Factor?

There are many detrimental effects a person can experience from being overweight or obese and new studies find that they may be potential contributors to the development of Alzheimer’s later in life.

There is particularly strong evidence for midlife obesity as a risk factor for AD [Alzheimer Disease]. A cross-sectional study published in Obesity found an inverse relationship between BMI and cognitive function among healthy late middle-aged adults, and various observational studies have reported that obesity in midlife increased the risk for late-life dementia.4 In research recently published in JAMA, high BMI in midlife was the only midlife vascular risk factor that demonstrated a significant association with increased late-life brain amyloid deposition (odds ratio, 2.06).5 (Source: Obesity and Alzheimer Disease: Exploring Risk Modification)

Learn more about these studies and their findings, including direct reference links to individual studies, in the full article here: “Obesity and Alzheimer Disease: Exploring Risk Modification.”

 

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